Adblock Plus for Edge is designed to block ads on Microsoft's latest browser.
The package only works on Windows 10 Anniversary Edition, as that includes the first build of Edge to support extensions.
(If you're not sure which version of Windows 10 you have, follow the download link anyway. If it's not available, Windows Store will warn you that "to use this, you need to upgrade Windows.")
Keep in mind that this is a beta, and not as reliable as other versions you might have tried. The developer explains:
"Adblock Plus for Microsoft Edge is still in early development stages and has known issues and limitations. While ads will be blocked of course, it is possible to experience undesired side effects on some websites and the number of filter subscriptions is limited. Microsoft and Adblock Plus are continuing to make improvements which you’ll see through automatic updates."
Adblock Plus's Edge edition needs some work, but that's no surprise for such an early edition, and given the developer's track record we're sure any issues will be resolved soon.